New service in Des Moines provides greater access to destinations across the Midwest and Eastern U.S.

DES MOINES, IA — Effective June 30, 2026, Jefferson Lines will launch enhanced intercity bus service connecting Des Moines with Williamsburg, Iowa City, Cedar Rapids, Waterloo, Dubuque and Chicago. The new service offers afternoon departures and easier connections to major U.S. cities.  

The new route strengthens transportation options throughout Iowa, Illinois and Minnesota while improving connections to Jefferson Lines’ national network. Travelers gain easier access to destinations beyond Iowa, including Minneapolis, Chicago and connections to numerous cities throughout the eastern United States.   

Passengers traveling from Des Moines will depart from the Intercity Bus Terminal, a centrally located transportation hub with nearby stops for local public transit. The location provides seamless access for travelers throughout Des Moines. 

By improving connections between key regional markets and surrounding communities, the enhanced service offers residents, students, business travelers and visitors a straightforward and reliable transportation option throughout the Midwest and beyond with new and improved departure times from Des Moines to Chicago.

Passengers will enjoy a range of modern travel conveniences with Jefferson Lines, including complimentary Wi-Fi, a real-time Bus Tracker and easy booking and rebooking through Jefferson Lines Customer Accounts. Travelers can also access services on the go with a dedicated mobile app for both iOS and Android devices. In addition, a responsive Customer Care team is available to provide support at every stage of the journey. 

Des Moines to Chicago fares start at $68.00. Book online with Jefferson Lines for the lowest fare: www.jeffersonlines.com.  

ABOUT JEFFERSON LINES

Jefferson Lines has connected communities with safe, affordable, and reliable bus travel since 1919. Our 17-state network connects to 2,000+ destinations nationwide, making travel easy and convenient across the Midwest and beyond. Follow along on social media for updates.