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Jefferson Lines Launches New Service in Chicago to Des Moines and Minneapolis

New service in Chicago provides greater access to destinations across the Midwest and Eastern U.S.

CHICAGO, IL — Effective June 30, 2026, Jefferson Lines will launch enhanced intercity bus service connecting Chicago with Dubuque, Minneapolis, Mason City, Waterloo, Cedar Rapids and Des Moines. 

The new route strengthens transportation options throughout Illinois, Iowa, and Minnesota while providing convenient connections to Jefferson Lines’ national network. Travelers will have expanded access to destinations beyond Minneapolis, including communities across Minnesota, North Dakota, South Dakota, Montana, and other points throughout Jefferson Lines’ Midwest network. 

Passengers traveling from Chicago will depart from 630 W Harrison St., Chicago, IL 60607, a conveniently located stop providing easy access for travelers in downtown Chicago and surrounding areas. The location offers a central departure point for passengers traveling to communities across Iowa, Minnesota, and beyond. 

By connecting key regional markets and surrounding communities, the enhanced service offers residents, students, business travelers, and visitors an affordable and reliable transportation option throughout the Midwest and beyond. 

Passengers will enjoy a range of modern travel conveniences with Jefferson Lines, including complimentary Wi-Fi, a real-time Bus Tracker, and easy booking and rebooking through Jefferson Lines Customer Accounts. Travelers can also access services on the go with a dedicated mobile app for both iOS and Android devices. In addition, a responsive Customer Care team is available to provide support at every stage of the journey. 

Chicago to Minneapolis fares start at $60.00. Book online with Jefferson Lines for the lowest fare: www.jeffersonlines.com 

ABOUT JEFFERSON LINES

Jefferson Lines has connected communities with safe, affordable, and reliable bus travel since 1919. Our 17-state network connects to 2,000+ destinations nationwide, making travel easy and convenient across the Midwest and beyond. Follow along on social media for updates.